GO:0007227 biological_process signal transduction downstream of smoothened
| PAG Title | GO:0007227 biological_process signal transduction downstream of smoothened |
| PAG ID | TAX016860 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway. |
| Species | Homo sapiens |
| nCoCo Score | 0 |
| Base PAG ID | TAX016860 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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